Yay for loss of cognition!
A small study indicates that changes in how alcohol is metabolized after surgery can speed its delivery into the bloodstream, resulting in earlier and higher peaks in blood-alcohol levels. Studying women who had undergonegastric bypass surgery, the researchers found that those who had consumed the equivalent of two drinks in a short period of time had blood-alcohol contents similar to women who had consumed four drinks but had not had the operation.
The research is published Aug. 5 in the journal JAMA Surgery.
"The findings tell us we need to warn patients who have gastric bypass surgery that they will experience changes in the way their bodies metabolize alcohol," said first author M. Yanina Pepino, PhD, an assistant professor of medicine in the Division of Geriatrics and Nutritional Science. "Consuming alcohol after surgery could put patients at risk for potentially serious problems, even if they consume only moderate amounts of alcohol."
Although this study included only women, it is likely that men who have gastric bypass surgery experience similar changes in how their bodies metabolize alcohol.
The researchers studied alcohol's effects in 17 obese women. Eight of the women had undergone Roux-en-Y gastric bypass surgery—the most common bariatric surgical procedure worldwide—one to five years before the study began. The other nine participants had not yet had the operation.
As part of the study, the women spent two days, about one week apart, at Washington University's Clinical Research Center. On one visit, each woman randomly consumed either the equivalent of two alcoholic drinks or two nonalcoholic beverages during a 10-minute period. At the second visit, each was given the beverages not received during the first visit. At both visits, the researchers measured the women's blood-alcohol contents and used a survey to assess their feelings of drunkenness.
The women in the gastric bypass group had an average body mass index (BMI) of 30, which is considered obese, but it compared with an average BMI of 44 for the women who had not yet had the surgery. Among those who had not undergone surgery, blood-alcohol content peaked about 25 minutes after they finished consuming the alcohol and measured 0.60. In women who had the surgery, blood-alcohol content peaked at 5 minutes after drinking and reached 1.10, significantly above the legal driving limit of 0.80.
"These findings have important public safety and clinical implications," said senior investigator Samuel Klein, MD, the William H. Danforth Professor of Medicine and director of the Center for Human Nutrition. "After just two drinks, the blood-alcohol content in the surgery group exceeded the legal driving limit for 30 minutes, but the levels in the other group never reached the legal limit.
"The peak blood-alcohol content in the surgery group also met the criteria that the National Institute on Alcohol Abuse and Alcoholism uses to define an episode of binge drinking, which is a risk factor for developing alcohol problems."
Women who had undergone gastric bypass also reported feeling the effects of alcohol earlier and for longer periods of time than women who had not had the surgery.
The study is not the first to find that gastric bypass surgery can alter alcohol metabolism, but Pepino said it is significant because earlier studies had measured blood alcohol less vigorously and were less clear about the extent of the changes in alcohol metabolism.
"The women who had the surgery only received the equivalent of two drinks, but it was as if they had consumed twice that amount," she said. "Consuming alcohol after surgery the way one did before the operation could put patients at risk for potentially serious consequences, even when they drink only moderate amounts of alcohol."
More information: Pepino MY, Okunade AL, Eagon JC, Bartholow BD, Bucholz K, Klein S. Effect of Roux-ex-Y gastric bypass surgery: converting 2 alcoholic drinks to 4. JAMA Surgery, published online Aug. 5, 2015. DOI: 10.1001/jamasurg.2015.1884
Long-term followup of type of bariatric surgery finds regain of weight, decrease in diabetes remission
While undergoing laparoscopic sleeve gastrectomy induced weight loss and improvements in obesity-related disorders, long-term followup shows significant weight regain and a decrease in remission rates of diabetes and, to a lesser extent, other obesity-related disorders over time, according to a study published online by JAMA Surgery.
Obesity was recognized as a global epidemic by the World Health Organization 15 years ago and rates of obesity have since been increasing. Obesity is currently considered a severe health hazard and a risk factor fordiabetes mellitus, hypertension, abnormal lipid levels, heart failure, and other related disorders. Bariatric procedures are reportedly the most effective strategy to induce weight loss compared with nonsurgical interventions. Laparoscopic sleeve gastrectomy (LSG) is a common and efficient bariatric procedure with increasing popularity in the Western world during the last few years, but data on its long-term effect on obesity-related disorders are scarce, according to background information in the article.
Andrei Keidar, M.D., of Beilinson Hospital, Petah Tikva, Israel, and colleagues collected data on all patients undergoing LSGs performed by the same team at a university hospital between April 2006 and February 2013, including demographic details, weight followup, blood test results, and information on medications and comorbidities.
A total of 443 LSGs were performed. Complete data were available for 54 percent of patients at the 1-year follow-up, for 49 percent of patients at the 3-year follow-up, and for 70 percent of patients at the 5-year follow-up. The percentage of excess weight loss was 77 percent, 70 percent, and 56 percent, at years 1, 3 and 5, respectively; complete remission of diabetes was maintained in 51 percent, 38 percent, and 20 percent, respectively, and remission of hypertension was maintained in 46 percent, 48 percent, and 46 percent, respectively.
The decrease of low-density lipoprotein cholesterol level was significant only at years 1 and 3. The changes in total cholesterol level (preoperatively and at 1, 3, and 5 years) did not reach statistical significance.
"The longer follow-up data revealed weight regain and a decrease in remission rates for type 2 diabetes mellitusand other obesity-related comorbidities. These data should be taken into consideration in the decision-making process for the most appropriate operation for a given obese patient," the authors write.
More information: JAMA Surgery. Published online August 5, 2015. DOI: 10.1001/jamasurg.2015.2202
And I sigh. I feel like this is asking for an eating disorder, but what do I know.
The U.S. Food and Drug Administration today approved a new balloon device to treat obesity without the need for invasive surgery. The ReShape Integrated Dual Balloon System (ReShape Dual Balloon) is intended to facilitate weight loss in obese adult patients. The device likely works by occupying space in the stomach, which may trigger feelings of fullness, or by other mechanisms that are not yet understood.
The ReShape Dual Balloon device is delivered into the stomach via the mouth through a minimally invasive endoscopic procedure. The outpatient procedure usually takes less than 30 minutes while a patient is under mild sedation. Once in place, the balloon device is inflated with a sterile solution, which takes up room in the stomach.
The device does not change or alter the stomach’s natural anatomy. Patients are advised to follow a medically supervised diet and exercise plan to augment their weight loss efforts while using the ReShape Dual Balloon and to maintain their weight loss following its removal. It is meant to be temporary and should be removed six months after it is inserted.
“For those with obesity, significant weight loss and maintenance of that weight loss often requires a combination of solutions including efforts to improve diet and exercise habits,” said William Maisel, M.D., M.P.H., acting director of the Office of Device Evaluation at the FDA’s Center for Devices and Radiological Health. “This new balloon device provides doctors and patients with a new non-surgical option that can be quickly implanted, is non-permanent, and can be easily removed.”
Something I feel like we already knew? Sigh. Please read.
PR from The Obesity Society -
Alcohol Sensitizes Brain Response to Food Aromas and Increases Food Intake in Women, Research Shows
First study of its kind ties hypothalamus, in addition to the gut, to the aperitif phenomenon
SILVER SPRING, MD – The first study of its kind measuring the brain's role in mediating caloric intake following alcohol consumption among women shows that alcohol exposure sensitizes the brain's response to food aromas and increases caloric intake. The research, led by William J. A. Eiler II, PhD, of the Indiana University School of Medicine's Departments of Medicine and Neurology, adds to the current body of knowledge that alcohol increases food intake, also known as the "aperitif effect," but shows this increased intake does not rely entirely on the oral ingestion of alcohol and its absorption through the gut. The study is published in the July issue of the journal Obesity published by The Obesity Society (TOS).
"The brain, absent contributions from the gut, can play a vital role in regulating food intake. Our study found that alcohol exposure can both increase the brain's sensitivity to external food cues, like aromas, and result in greater food consumption," said Dr. Eiler. "Many alcoholic beverages already include empty calories, and when you combine those calories with the aperitif effect, it can lead to energy imbalance and possibly weight gain."
Researchers conducted the study in 35 non-vegetarian, non-smoking women at a healthy weight. To test the direct effects of alcohol on the brain, researchers circumvented the digestive system by exposing each participant to intravenously administered alcohol at one study visit and then to a placebo (saline) on another study visit, prior to eating. Participants were observed, and brain responses to food and non-food aromas were measured using blood oxygenation level dependent (BOLD) response via fMRI scans. After imaging, participants were offered a lunch choice between pasta with Italian meat sauce and beef and noodles.
When participants received intravenous alcohol, they ate more food at lunch, on average, compared to when they were given the placebo. However, there were individual differences, with one-third of participants eating less after alcohol exposure when compared to the placebo exposure. In addition to changes in consumption, the area of the brain responsible for certain metabolic processes, thehypothalamus, also responded more to food odors, compared to non-food odors, after alcohol infusion vs. saline. The researchers concluded that the hypothalamus may therefore play a role in mediating the impact of alcohol exposure on our sensitivity to food cues, contributing to the aperitif phenomenon.
"This research helps us to further understand the neural pathways involved in the relationship between food consumption and alcohol," said Martin Binks, PhD, FTOS, TOS Secretary Treasurer and Associate Professor of Nutrition Sciences at Texas Tech University. "Often, the relationship between alcohol on eating is oversimplified; this study unveils a potentially more complex process in need of further study."
Study authors agree and call for further research into the mechanism by which the hypothalamus affects food reward.
"Today, nearly two-thirds of adults in the U.S. consume alcohol, with wine consumption rising, which reinforces the need to better understand how alcohol can contribute to overeating," continued Dr. Binks.
Read the full article in Obesity here.
What the who!?
'Anyone with a functioning brain' makes sure they look good in a bikini
Clipped from Raw Story -
“If you are offended by an ad with a woman on it or a hot girl or a hot guy then seek therapy,” Fox News host Jedediah Bila advised on Monday. “I mean, go to a therapist. There’s something wrong with you.”
“At this time of year, anyone with a functioning brain asks themselves that question, ‘Are you beach body ready?'” Tantaros insisted. “In fact, I ask myself that question every single day. And I bet you people who have a problem with this ad going into summer time are not beach body ready.”
“It’s such a bunch of bull,” the Fox News host said of critics. “Everyone wants to know if they look good in a swimsuit!”
“You should grow up wanting to look like that anyway,” guest host Chris Plante quipped.
This procedure is now done where Bob and I both had our weight loss surgeries 11.5 years ago. I recall posting about it years ago when it was in testing.
I think it's a neat idea.
If you think about weight loss surgery, there are three main options: Gastric Bypass, the Lap Band, and the Gastric Sleeve. But there haven’t been any other weight loss procedures approved by the FDA for over ten years, that is, until now. Back in January the government agency approved a new device that’s less complicated, safe, and effective.
“Most all of my life I have been overweight.” Mike Magnant from Carver loves to spend time on the tugboat he built, but the extra pounds he carried around took a toll. “High blood pressure, high cholesterol, pains in my legs and pains in my knees,” Mike explains. “I couldn’t do the things I wanted to do.”
He tried a slew of diets but every time, he regained the weight and then some.
At a max of 291 pounds, he knew he had to do something drastic. So Mike enrolled in a clinical trial at Tufts Medical Center studying a new minimally invasive weight loss system called vBloc Therapy by EnteroMedics.
Like a pacemaker, the device is inserted under the skin and electrodes are fed into the abdomen and secured around the vagus nerve which controls hunger. Dr. Sajani Shah, a surgeon at Tufts Medical Center who specializes in weight loss surgery, explains, “It blocks the nerve to the brain and basically tells patients that they’re less hungry and they get satiated for longer periods of time.”
About three years ago, Mike underwent the procedure with Dr. Shah. He went home the same day, back to work three days later, and has lost more than 70 pounds. He says he still enjoys a good meal, but just doesn’t eat as much. He doesn’t feel hungry.
Studies showed patients lost about 30% of their excess weight. “If diet and exercise aren’t working because unfortunately the yo-yo dieting is sometimes hard,” says Dr. Shah, “But they don’t want the other things we have to offer, like the bypass or the sleeve because it’s really complicated, then this is a great, safe alternative for patients to treat their obesity.”
And even though the system is reversible, Mike says it’s his to keep. “I’ve told them. I’m never giving it back. I don’t want anybody to take it back,” he smiles.
Mike says not only has he maintained his weight loss but he has saved a lot of money. He takes fewer medications for blood pressure and cholesterol, has fewer doctors’ appointments, eats less food, and spends less on clothing because now he doesn’t have to buy at the big and tall stores.
Just last week, Tufts Medical Center became the first hospital in the country to perform the surgery on a patient outside of a clinical trial.
A post by a Facebook friend the other day got me thinking about blogging. It seems that many of us who used to Write All The Time for ourselves, have stopped. Why is that? Why is it that blogging has become a chore? Why did we start writing in the first place and what changed?
I will tell you what happened: PEOPLE GOT GREEDY. For me, I started blogging because I needed an outlet that would "listen" neutrally. The faceless internet seemed like a good idea.
As I wrote, somehow I got an audience, and an audience creates attention, and attention sends advertisers. I took on advertisements and started earning a part time living from this blog. Heck, I started a blog about blogging because I made a GOOD living from it for a very short time.
The thing is: I have very strong opinions and cannot be paid to be swayed. It tears me up when I read sponsored posts and Tweets and Facebook plugs from other bloggers after they've been given ad money and the posts are no longer in their voice.
Some blogs and connected social media become nothing but pitches. #spon #ad
Where did genuine bloggers go?! Where are you?!
I didn't want to become that, and honestly I hate being called a shill. I used to enjoy writing about product because I USED IT or I LOVED IT or my favorite: I hated it.
I have lost that because everyone and their Mama is overexposing EVERYTHING hoping to get paid. I did get paid. I still have a trickle of advertising, but I can't push it as hard as I "could" because I feel like it alienates those who read my stuff (...for whatever reason they do?) and feel pressured. Bloggers who used to "connect" with me, I realize, I am no longer useful to them if they can't use me. It's sad.
Sometimes I felt like a fake by posting about products I didn't really like. I lost my oomph and advertisers took notice and dumped me. Sadly, sometimes I think it was a relief. I'm not your salesperson. You didn't hire me.
I think these days, most sponsored content needs to come organically. Why do "we" push so hard to be paid to do what we were already doing for free, for ourselves? If someone wants to pay me to be MYSELF, bring it. I can't change or remain silent because you don't like me as I am.
I feel like I have censored myself for so long because I have been afraid of the ADVERTISERS getting mad.
No more. Fuck them. If they're paying me to share product, it's because I AM WORTH IT, and if they choose not to? That's fine too.
Sorry. If I write about your product, it's because I USE IT, I LOVE IT or IT SUCKS. There's no ulterior motive, unless I specifically state that there is. ;)
This video was made as a part of The Bridge Exchange, an exchange program for young artists between VidCon and the Brave New Voices Festival to bridge the spoken word and online video communities. Learn about the project here: http://bit.ly/BridgeExchangeVideoPlay...
Watch more videos here:
Seize Her by Lerato Lee Mokobe: http://bit.ly/SeizeHer
Hereditary by Rhiannon McGavin: http://bit.ly/Hereditary-Poem
Dear Winchat by Belinda Zwahi: http://bit.ly/DearWinchat
Fat Kid by Travis Thompson: http://bit.ly/FatKidPoem
Dear Pluto by Amelia Xanthe: http://bit.ly/DearPluto
Princess by Arianna Burrell: http://bit.ly/PrincessPoem
Monster by Unique Hughley: http://bit.ly/MonsterPoem
More about VidCon: http://vidcon.com/
More about Brave New Voices: http://youthspeaks.org/bravenewvoices/
More about The Bridge Exchange:
Written by Travis Thompson
Video Directors - Jackson Adams, Bayan Joonam, Georgia Koch
Program Producer - Jose Vadi
Editor - Andy Golibersuch
Watching now. I know many in the weight loss surgery community deal with epileptic syndromes as well.
Fat, Naked & Unashamed: The Adipositivity Project by TIME Magazine
Oddly enough last year was my best in terms of weight loss and weight maintenance after my roux en y gastric bypass now eleven years ago.
I just searched the blog for my yearly *cringe* "surgiversary" updates and it appears it really was.
"Best." I maintained a nearly-normal bodyweight for half of the year, guys. If I look back on my averages over the last ten years, the weight is smack-dab in the middle of average. I am just that.
I started out the year at my near lowest, while using the gym and eating decently. My goal had been to continue that - and ignore weight if I could add muscle tone.
One of the most common questions I get inboxed to me is: What Do You Eat Everyday - What Do You Do?! Here is the thing: PEOPLE VARY DRASTICALLY. I realized that my intake vs. output is a delicate balance.
Here's my intake for the most part of the last 90 days:
This looks mostly like this, with days of "Want pizza for dinner? Who wants mozzarella sticks?" Once a week. I eat very little meat, though I am still cooking it a couple times a week for the family.
- Coffee - unsweetened almond milk - cocoa powder
- Frozen tofu based meal, other
- Leftovers from dinner or
- Soup or salad or
- Bread + cheese
- Chickpeas, whole grain crackers, cheese, veggie burrito
- Protein, veggie, carb - whatever is made for the family or...
- Frozen vegan meal
- More dinner, usually, I honestly don't eat at dinner time... I eat before bed. I might have a few bites at dinner time, especially if I am cooking, and then I don't want anything.
This isn't much different than my eating of the year before - and I maintain my weight at this level of calories. I would assume I eat about 1500 - 1700 most days with days lower, and days higher (rare).
I actually lose weight at this intake if I am moving enough.
Disclaimer, BMI SUCKS and I have NEVER been in the normal category for more than two minutes because I am SHORT AND I AM SHRINKING so if I want to EAT, I HAVE TO MOVE MY ASS.
I was. I'm not. No excuses.
My intentions were good, but life always seems to have different plans.
I developed some super fun back pain that coincided with less time at the gym (...yes I think movement HELPS pain, but getting past pain to MOVE is now the problem!) and was diagnosed with some degenerative disc disease. My time working out was cut drastically with my spouse's work schedule changing - kid's school schedules and just having no means to go. Adding the lack of gym time to pain = Beth not moving her ass because it hurts = Beth not moving. I started slugging out at home from August (...when the schedule changed) to this winter. I hate to whine because Everybody Huuuurttttts. I'm also super realistic and I know I'm getting older, and it is unlikely that my back will Get Better at this age. It isn't going to benefit me to complain about it now because it's going to get worse with time.
Grinding along through back pain is difficult though, when it makes every part of your day a little more complicated - you'd think just sitting would be restful - easy. Sitting here is the most painful part of my day aside from attempting to sleep laying down, I live in a series of twitchy z-z-z-zaps. If I could pace all day long, I'd be fine.
And I just may start doing that.
Why? *changing tenses, writing badly but writing*
There was a single motivation -- I got on the scale after knowing that I was not fitting in my size medium running pants. THEY SQUISHED ME LIKE A SAUSAGE. I knew I had gained weight, I could see it - but - I kept squishing into them. So what if my legs are more puffy? Whatever.
And then my boobs. MY BOOBS. I didn't HAVE ANY, and a few weeks ago I'm all - O - O - and WHY DO THEY HURT I'd better start my cycle RIGHT NOW or I am going to cry and I just might cry right now or throw up.
I'll save you the dramatic implosion that occurred after three of those, but I've been to the MD twice, and I see a maternal-fetal medicine doctor tomorrow. I was not planning this, obviously, nor was I telling anyone, but a certain spouse outed me - and a lot of people took it as a joke.
I don't find it funny.
I've got this. I have never had a pregnancy WHILE on anti-epileptic medications, so that is of course of concern as I CANNOT be unmedicated and live safely. If you recall, my seizure activity became evident during my first post-RNY pregnancy and it was undiagnosed for a very long time. Also, apparently, I AM OLD. I am "Of Advanced Maternal Age."
ADVANCED. AGE. 3-5. This was the year, that I told my husband, I think we are old enough to have kids now. Forget that my oldest is the same age as I was when I got pregnant with her.
She said, "Well, at least it isn't me." Yes, thanks for that.
Grandma MM doesn't really have a ring to it. And I think my mother would explode.
HOW TO BECOME GLUTEN INTOLERANT FEELING ALONE AND LEFT OUT? HERE'S HOW TO BECOME GLUTEN INTOLERANT JUST LIKE YOUR FRIENDS.
So many parallels to the weight loss communities! I LOVE THIS.
How to prevent your stomach from stretching after weight loss surgery
- Exercising for four hours a day and following a strict diet can yield the same results as weight loss surgery, a leading doctor has claimed.
- Dr Robert Huizenga, of UCLA, says his extreme diet and exercise plan should replace bariatric surgery as a treatment for obesity.
- He says bariatric surgery is expensive and carries risks of death, muscle loss, bone thinning and mental health issues.
- His 'Biggest Loser' weight loss plan, which was made famous by the hit TV show of the same name, helps people lose the same amount of weight and is cheaper than surgery, he claims
- Read more: http://www.dailymail.co.uk/health/article-3014400/Weight-loss-surgery-waste-time-results-dieting-exercising-FOUR-hours-day-leading-expert-claims.html#ixzz3VgUVnXve
Dr. H says that "we" watch TV for four hours day, surely we have time to exercise that long, but FRANKLY, I DON'T WANT TO.
I am LAZY.
Do you honestly think I would have even considered it at my former size at ALL? NO freaking way. I am in a normal body weight range right now and there is zero point zero chance of getting me to exercise aerobically four hours daily -- at 320 lbs -- I would have sooner had weight loss surgery -- and I DID. Eleven years ago. LOL. It worked.
If there were any means to get my ass back to the gym and motivated it is reading things like THIS and pushing through back pain and tearing up my stupid excuses. BLAH BLAH BLAH BETH, I DON'T CARE THAT YOU CAN'T DRIVE YOU WILL WALK TO THE GYM AND DO IT ...
The FIT Treadmill Score is calculated using the patient’s age, gender, fitness level measured by METs, and peak heart rate reached during exercise. Researchers found these four factors to be the greatest predictors of mortality risk. After the research team accounted for other important variables, such as diabetes and family history of premature deaths, they determined fitness level to be the single most important predictor of death and survival.
“The notion that being in good physical shape portends lower death risk is by no means new, but we wanted to quantify that risk precisely by age, gender, and fitness level, and do so with an elegantly simple equation that requires no additional fancy testing beyond the standard stress test,” said Dr. Haitham Ahmed, a cardiology fellow at the Johns Hopkins University School of Medicine.
FIT Treadmill Scores ranged from negative 200 to positive 200 — participants over 0 had a lower mortality risk while participants under 0 has a higher mortality risk. Participants with a score between negative 100 and 0 had an 11 percent risk for dying in the next 10 years compared to three percent among participants with a scare between 0 and positive 100. Participants with a score lower than negative 100 had a 38 percent mortality risk compared to two percent among those who scored positive 100 or higher.
To determine which routinely collected exercise test variables most strongly correlate with survival and to derive a fitness risk score that can be used to predict 10-year survival.
Patients and Methods
This was a retrospective cohort study of 58,020 adults aged 18 to 96 years who were free of established heart disease and were referred for an exercise stress test from January 1, 1991, through May 31, 2009. Demographic, clinical, exercise, and mortality data were collected on all patients as part of the Henry Ford ExercIse Testing (FIT) Project. Cox proportional hazards models were used to identify exercise test variables most predictive of survival. A “FIT Treadmill Score” was then derived from the β coefficients of the model with the highest survival discrimination.
The median age of the 58,020 participants was 53 years (interquartile range, 45-62 years), and 28,201 (49%) were female. Over a median of 10 years (interquartile range, 8-14 years), 6456 patients (11%) died. After age and sex, peak metabolic equivalents of task and percentage of maximum predicted heart rate achieved were most highly predictive of survival (P<.001). Subsequent addition of baseline blood pressure and heart rate, change in vital signs, double product, and risk factor data did not further improve survival discrimination. The FIT Treadmill Score, calculated as [percentage of maximum predicted heart rate + 12(metabolic equivalents of task) – 4(age) + 43 if female], ranged from −200 to 200 across the cohort, was near normally distributed, and was found to be highly predictive of 10-year survival (Harrell C statistic, 0.811).
The FIT Treadmill Score is easily attainable from any standard exercise test and translates basic treadmill performance measures into a fitness-related mortality risk score. The FIT Treadmill Score should be validated in external populations.
Now do it.
But. But. But.
FAAAAAHTS or Gastrointestinal colonization with methanogens increases difficulty of losing weight after bariatric surgery
I feel like we knew this - have you lived with a gastric bypass or duodenal switch patient for a period of time? I'm just saying, those of us with altered bariatric intestines LIVE with "MARSH ASS." Welcome to the world of pre-biotics, probiotics, fart-smell-better products and I kid you not, LINED UNDERWEAR.
Hey, I never said I was a professional. Read the studies.
What is a methanogen? Wisegeek says --
"Methanogens are a type of microorganism that produces methane as a byproduct of metabolismin conditions of very low oxygen. They are often present in bogs, swamps, and other wetlands, where the methane they produce is known as "marsh gas." Methanogens also exist in the guts of some animals, including cows and humans, where they contribute to the methane content of flatulence. Though they were once classified as Archaebacteria, methanogens are now classified as Archaea, distinct from Bacteria.
Some types of methanogen, including those of the Methanopyrus genus, are extremophiles, organisms that thrive in conditions most living things could not survive in, such as hot springs, hydrothermal vents, hot desert soil, and deep subterranean environments. Others, such as those of the Methanocaldococcus genus, are mesophiles, meaning they thrive best in moderate temperatures. Methanobrevibacter smithii is the prominent methanogen in the human gut, where it helps digest polysaccharides, or complex sugars."
Gut bacteria may decrease weight loss from bariatric surgery March 6, 2015
Source: Cedars-Sinai Medical Center
The benefits of weight loss surgery, along with a treatment plan that includes exercise and dietary changes, are well documented. In addition to a significant decrease in body mass, many patients find their risk factors for heart disease are drastically lowered and blood sugar regulation is improved for those with Type 2 diabetes.
Some patients, however, do not experience the optimal weight loss from bariatric surgery. The presence of a specific methane gas-producing organism in the gastrointestinal tract may account for a decrease in optimal weight loss, according to new research by Ruchi Mathur, MD, director of the Diabetes Outpatient Treatment and Education Center at Cedars-Sinai.
"We looked at 156 obese adults who either had Roux-en-Y bypass surgery or received a gastric sleeve. Four months after surgery we gave them a breath test, which provides a way of measuring gases produced by microbes in the gut," said Mathur. "We found that those whose breath test revealed higher concentrations of both methane and hydrogen were the ones who had the lowest percentage of weight loss and lowest reduction in BMI (body mass index) when compared to others in the study."
The methane-producing microorganism methanobrevibacter smithii is the biggest maker of methane in the gut, says Mathur, and may be the culprit thwarting significant weight loss in bariatric patient. Mathur and her colleagues are conducting further studies to explore the role this organism plays in human metabolism.
While that research continues, bariatric patients may still have options to improve weight loss after surgery.
"Identifying individuals with this pattern of intestinal gas production may allow for interventions through diet. In the future there may be therapeutic drugs that can improve a patient's post-surgical course and help them achieve optimal weight loss," said Mathur.
The study, "Intestinal Methane Production is Associated with Decreased Weight Loss Following Bariatric Surgery" was done in collaboration with the Mayo Clinic. The paper is being presented by Mathur Thursday, March 5, at the 97th annual meeting of the Endocrine Society in San Diego.
Clearly I do not have a problem with this.
There are some words I despise. Dump is one.